Activating Compound | Comment | Organism | Structure |
---|---|---|---|
APE1 | APE1, a human homolog of Escherichia coli exonuclease III Xth stimulates under conditions of Vmax | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme is inhibited by the product of its DNA N-glycosylase activity directed against Tg:G, the AP:G site, but not inhibited by the AP:A site arising from release of Tg from Tg:A | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA | Homo sapiens | - |
fragments of DNA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DNA | - |
Homo sapiens | fragments of DNA | - |
? | |
DNA | rate of AP lyase-mediated strand cleavage is much slower than the rate of DNA N-glycoxsylase-mediated base release | Homo sapiens | fragments of DNA | - |
? |