Cloned (Comment) | Organism |
---|---|
- |
Neurospora crassa |
Protein Variants | Comment | Organism |
---|---|---|
H106A | activity 10fold decreased | Neurospora crassa |
H17A | activity 20fold decreased | Neurospora crassa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(6S)-6-fluoro-5-enolpyruvylshikimate 3-phosphate | competitive inhibitor | Neurospora crassa | |
O2 | activity only in anaerobic conditions | Streptococcus pneumoniae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-enolpyruvylshikimate 3-phosphate | Neurospora crassa | - |
chorismate + phosphate | - |
? | |
5-enolpyruvylshikimate 3-phosphate | Salmonella enterica | - |
chorismate + phosphate | - |
? | |
5-enolpyruvylshikimate 3-phosphate | Yersinia enterocolitica | - |
chorismate + phosphate | - |
? | |
5-enolpyruvylshikimate 3-phosphate | Brucella suis | - |
chorismate + phosphate | - |
? | |
5-enolpyruvylshikimate-3-phosphate | Streptococcus pneumoniae | - |
chorismate + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Brucella suis | - |
- |
- |
Neurospora crassa | - |
- |
- |
Salmonella enterica | - |
- |
- |
Streptococcus pneumoniae | - |
- |
- |
Yersinia enterocolitica | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(6S)-6-fluoro-5-enolpyruvylshikimate 3-phosphate | converion rate between 270 and 370 times slower than natural substrate conversion | Streptococcus pneumoniae | 6-fluorochorismate + phosphate | - |
? | |
5-enolpyruvylshikimate 3-phosphate | - |
Neurospora crassa | chorismate + phosphate | - |
? | |
5-enolpyruvylshikimate 3-phosphate | - |
Salmonella enterica | chorismate + phosphate | - |
? | |
5-enolpyruvylshikimate 3-phosphate | - |
Yersinia enterocolitica | chorismate + phosphate | - |
? | |
5-enolpyruvylshikimate 3-phosphate | - |
Brucella suis | chorismate + phosphate | - |
? | |
5-enolpyruvylshikimate-3-phosphate | - |
Streptococcus pneumoniae | chorismate + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
chorismate synthase | - |
Neurospora crassa |
chorismate synthase | - |
Streptococcus pneumoniae |
chorismate synthase | - |
Salmonella enterica |
chorismate synthase | - |
Yersinia enterocolitica |
chorismate synthase | - |
Brucella suis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FMN | - |
Neurospora crassa | |
FMN | - |
Streptococcus pneumoniae | |
FMN | - |
Salmonella enterica | |
FMN | - |
Yersinia enterocolitica | |
FMN | - |
Brucella suis |