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Literature summary for 4.2.3.4 extracted from

  • Ran, N.; Frost, J.W.
    Directed evolution of 2-keto-3-deoxy-6-phosphogalactonate aldolase to replace 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthase (2007), J. Am. Chem. Soc., 129, 6130-6139.
    View publication on PubMed
Search for more literature for 4.2.3.4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate Escherichia coli
-
 3-dehydroquinate + phosphate
-
 ir

Organism

Organism UniProt Comment Textmining
Escherichia coli P07639
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.009
-
 strain NR7, plasmid pKL4.79, activity is measured for cells removed from the fermentor 24 h after inoculation Escherichia coli
0.01
-
 strain NR7, plasmid pKL4.79, activity is measured for cells removed from the fermentor 36 h after inoculation Escherichia coli
0.011
-
 strain NR7, plasmid pKL4.79, activity is measured for cells removed from the fermentor 48 h after inoculation Escherichia coli
0.015
-
 strain NR7, plasmid pNR8.075, activity is measured for cells removed from the fermentor 24 h after inoculation Escherichia coli
0.016
-
 strain NR7, plasmid pNR8.075, activity is measured for cells removed from the fermentor 36 h after inoculation Escherichia coli
0.016
-
 strain NR7, plasmid pNR8.075, activity is measured for cells removed from the fermentor 48 h after inoculation Escherichia coli
0.016
-
 strain NR7, plasmid pNR8.288, activity is measured for cells removed from the fermentor 48 h after inoculation Escherichia coli
0.017
-
 strain NR7, plasmid pNR8.288, activity is measured for cells removed from the fermentor 24 h after inoculation Escherichia coli
0.017
-
 strain NR7, plasmid pNR8.288, activity is measured for cells removed from the fermentor 36 h after inoculation Escherichia coli
0.022
-
 strain NR7, plasmid pNR9.127, activity is measured for cells removed from the fermentor 36 h after inoculation Escherichia coli
0.023
-
 strain NR7, plasmid pNR8.294, activity is measured for cells removed from the fermentor 48 h after inoculation Escherichia coli
0.024
-
 strain NR7, plasmid pNR9.127, activity is measured for cells removed from the fermentor 48 h after inoculation Escherichia coli
0.027
-
 strain NR7, plasmid pNR9.127, activity is measured for cells removed from the fermentor 24 h after inoculation Escherichia coli
0.039
-
 strain NR7, plasmid pNR8.294, activity is measured for cells removed from the fermentor 36 h after inoculation Escherichia coli
0.043
-
 strain NR7, plasmid pNR8.294, activity is measured for cells removed from the fermentor 24 h after inoculation Escherichia coli
0.53
-
 strain NR7, plasmid pNR9.056, activity is measured for cells removed from the fermentor 24 h after inoculation Escherichia coli
0.92
-
 strain NR7, plasmid pNR9.056, activity is measured for cells removed from the fermentor 36 h after inoculation Escherichia coli
1.17
-
 strain NR7, plasmid pNR9.056, activity is measured for cells removed from the fermentor 48 h after inoculation Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate
-
 Escherichia coli 3-dehydroquinate + phosphate
-
 ir

Synonyms

Synonyms Comment Organism
3-dehydroquinate synthase
-
 Escherichia coli
DHQ synthase
-
 Escherichia coli

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 activity assay Escherichia coli