Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.2.3.4 extracted from

  • Lambert, J.M.; Boocock, M.R.; Coggins, J.R.
    The 3-dehydroquinate synthase activity of the pentafunctional arom enzyme complex of Neurospora crassa is Zn2+-dependent (1985), Biochem. J., 226, 817-829.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.3.4

Inhibitors

Inhibitors Comment Organism Structure
1,10-phenanthroline
-
 Neurospora crassa
bistrispropane
-
 Neurospora crassa
Cu2+
-
 Neurospora crassa
dithiothreitol
-
 Neurospora crassa
EDTA
-
 Neurospora crassa
Fe2+
-
 Neurospora crassa
NADH
-
 Neurospora crassa
Ni2+
-
 Neurospora crassa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0014
-
 3-deoxy-D-arabino-heptulosonic acid 7-phosphate
-
 Neurospora crassa

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+
-
 Neurospora crassa

Organism

Organism UniProt Comment Textmining
Neurospora crassa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
arom-multienzyme complex Neurospora crassa

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Neurospora crassa

Storage Stability

Storage Stability Organism
-20°C, more than 1 year Neurospora crassa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-deoxy-D-arabino-heptulosonic acid 7-phosphate
-
 Neurospora crassa 3-dehydroquinate + phosphate
-
 ?
3-deoxy-D-arabino-heptulosonic acid 7-phosphate
-
 Neurospora crassa 74-OR23-1A 3-dehydroquinate + phosphate
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
19
-
 3-deoxy-D-arabino-heptulosonic acid 7-phosphate
-
 Neurospora crassa

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Neurospora crassa