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Literature summary for 4.2.3.3 extracted from

  • Saadat, D.; Harrison, D.H.
    Mirroring perfection: the structure of methylglyoxal synthase complexed with the competitive inhibitor 2-phosphoglycolate (2000), Biochemistry, 39, 2950-2960.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
complexed with 2-phosphoglycolate, sitting drop vapor diffusion method Escherichia coli

Inhibitors

Inhibitors Comment Organism Structure
2-Phosphoglycolate inhibits Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli P0A731
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dihydroxyacetone phosphate
-
Escherichia coli methylglyoxal + phosphate
-
?
additional information enzyme is not capable of abstracting the C2 proton from glyceraldehyde phosphate, which is an absolute requirement for the function of MGS Escherichia coli ?
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?