Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli and in an engineered Streptomyces host.Recombinant SCLAV_p0490 forms insoluble proteins | Streptomyces cyslabdanicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(+)-copalyl diphosphate | Streptomyces cyslabdanicus | - |
labda-8(17),12,14-triene + diphosphate | - |
? | |
labda-7,13-dienyl diphosphate | Streptomyces cyslabdanicus | - |
labda-7,12,14-triene + diphosphate | - |
? | |
additional information | Streptomyces cyslabdanicus | the ionization of (+)-copalyl diphosphate or labda-7,13-dienyl diphosphate is initiated by the removal of diphosphate, and the resultant cation is then quenched by the deprotonation at H-12 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces cyslabdanicus | A0A0H5BN57 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(+)-copalyl diphosphate | - |
Streptomyces cyslabdanicus | labda-8(17),12,14-triene + diphosphate | - |
? | |
labda-7,13-dienyl diphosphate | - |
Streptomyces cyslabdanicus | labda-7,12,14-triene + diphosphate | - |
? | |
additional information | the ionization of (+)-copalyl diphosphate or labda-7,13-dienyl diphosphate is initiated by the removal of diphosphate, and the resultant cation is then quenched by the deprotonation at H-12 | Streptomyces cyslabdanicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CldD | - |
Streptomyces cyslabdanicus |
labdatriene synthase | - |
Streptomyces cyslabdanicus |
General Information | Comment | Organism |
---|---|---|
physiological function | in an engineered Streptomyces host, labda-8(17),13(16),14-triene is generated by coexpression of SCLAV_p0491 and diterpene synthase CldB | Streptomyces cyslabdanicus |