Application | Comment | Organism |
---|---|---|
medicine | chemotherapeutic agent against a range of cancers, including ovarian and breast cancer | Taxus brevifolia |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Taxus brevifolia |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
98300 | - |
calculation from amino acid sequence | Taxus brevifolia |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
geranylgeranyl diphosphate | Taxus brevifolia | catalyzes the first step in taxol biosynthesis | taxa-4,11-diene + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Taxus brevifolia | Q41594 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Taxus brevifolia |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
geranylgeranyl diphosphate | - |
Taxus brevifolia | taxa-4(5),11(12)-diene + diphosphate | - |
? | |
geranylgeranyl diphosphate | catalyzes the first step in taxol biosynthesis | Taxus brevifolia | taxa-4,11-diene + diphosphate | - |
? |