Literature summary for 4.2.3.131 extracted from

Brueckner, K.; Bozic, D.; Manzano, D.; Papaefthimiou, D.; Pateraki, I.; Scheler, U.; Ferrer, A.; de Vos, R.C.; Kanellis, A.K.; Tissier, A.
Characterization of two genes for the biosynthesis of abietane-type diterpenes in rosemary (Rosmarinus officinalis) glandular trichomes (2014), Phytochemistry, 101, 52-64.

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Cloned(Commentary)

Cloned (Comment)	Organism
-	Salvia rosmarinus

Organism

Organism	UniProt	Comment	Textmining
Salvia rosmarinus	W8QEG7	-	-
Salvia rosmarinus	W8QMF8	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
leaf	elevated expression in trichome of young leaf. Isoform KSL1 transcript level is less than 1% of expression of isoform KSL2	Salvia rosmarinus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(+)-copalyl diphosphate	-	Salvia rosmarinus	miltiradiene + diphosphate	products are abietatriene and miltiradiene, ratio of miltiradiene to abietatriene is 100:30. Miltiradiene spontaneously reacts to abietatriene	?

Synonyms

Synonyms	Comment	Organism
kaurene synthase-like 1	-	Salvia rosmarinus
kaurene synthase-like 2	-	Salvia rosmarinus
KSL1	-	Salvia rosmarinus
KSL2	-	Salvia rosmarinus

General Information

General Information	Comment	Organism
physiological function	Nicotiana benthamiana transient expression of copalyl diphosphate synthase CPS1 with isoform KSL1 results in the production of miltiradiene plus about 25% abietatriene	Salvia rosmarinus

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Release 2023.1 (January 2023)