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Literature summary for 4.2.3.106 extracted from

  • Booth, J.; Page, J.; Bohlmann, J.
    Terpene synthases from Cannabis sativa (2017), PLoS ONE, 12, e0173911 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene CsTPS6FN, sequence comparisons and phylogenetic analysis, RT-PCR expression analysis Cannabis sativa

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Cannabis sativa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
geranyl diphosphate Cannabis sativa
-
(E)-beta-ocimene + diphosphate
-
?

Organism

Organism UniProt Comment Textmining
Cannabis sativa A0A1V0QSH1 var. Finola
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information transcriptome analysis of trichomes of the cannabis hemp variety Finola reveals sequences of all stages of terpene biosynthesis. Major terpene compounds such as beta-myrcene, (E)-beta-ocimene, (-)-limonene, (+)-alpha-pinene, beta-caryophyllene, and alpha-humulene. Transcripts associated with terpene biosynthesis are highly expressed in trichomes compared to non-resin producing tissues. Relative composition of terpene profiles in Cannabis sativa var. Finola pistillate flowers, overview Cannabis sativa
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trichome glandular Cannabis sativa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
geranyl diphosphate
-
Cannabis sativa (E)-beta-ocimene + diphosphate
-
?
additional information the enzyme shows no activity with farnesyl diphosphate. Reaction products are identified by GC-MS analysis Cannabis sativa ?
-
?

Synonyms

Synonyms Comment Organism
CsTPS6FN
-
Cannabis sativa
CsTPS6PK
-
Cannabis sativa

General Information

General Information Comment Organism
evolution the enzyme is a member of the terpene synthase (TPS) superfamily, CsTPSFN TPS-b subfamily Cannabis sativa
metabolism transcriptome analysis of trichomes of the cannabis hemp variety Finola reveal sequences of all stages of terpene biosynthesis. Nine cannabis terpene synthases (CsTPS) are identified in subfamilies TPS-a and TPS-b. Functional characterization identified mono- and sesqui-TPS, whose products collectively comprise most of the terpenes of Finola resin, including major compounds such as beta-myrcene, (E)-beta-ocimene, (-)-limonene, (+)-alpha-pinene, beta-caryophyllene, and alpha-humulene Cannabis sativa