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Literature summary for 4.2.3.1 extracted from

  • Thoen, A.; Rognes, S.E.; Aarnes, H.
    Biosynthesis of threonine from homoserine in pea seedlings. II. Threonine synthase (1978), Plant Sci. Lett., 13, 113-119.
No PubMed abstract available
Search for more literature for 4.2.3.1

Activating Compound

Activating Compound Comment Organism Structure
S-adenosylmethionine allosteric activator, 4fold increase of Vmax, 3.3fold decrease of substrate Km at 0.4 mM Pisum sativum

Inhibitors

Inhibitors Comment Organism Structure
L-cysteine 80% inhibition at 1 mM in presence of S-adenosylmethionine Pisum sativum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3 2.7 O-phosphohomoserine
-
 Pisum sativum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
190000
-
 gel filtration Pisum sativum

Organism

Organism UniProt Comment Textmining
Pisum sativum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Pisum sativum

Source Tissue

Source Tissue Comment Organism Textmining
seedling
-
 Pisum sativum
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.012
-
-
 Pisum sativum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
O-phospho-L-homoserine + H2O
-
 Pisum sativum L-threonine + phosphate
-
 ir

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
-
 Pisum sativum

pH Range

pH Minimum pH Maximum Comment Organism
6.8 8.4
-
 Pisum sativum

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate maximal activity at 0.4-1.0 mM Pisum sativum
pyridoxal 5'-phosphate required cofactor Pisum sativum