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Literature summary for 4.2.2.7 extracted from

  • Wu, J.; Zhang, C.; Mei, X.; Li, Y.; Xing, X.H.
    Controllable production of low molecular weight heparins by combinations of heparinase I/II/III (2014), Carbohydr. Polym., 101, 484-492.
    View publication on PubMed
Search for more literature for 4.2.2.7

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0468
-
 heparin isoform HepII, pH 7.4, 30°C Pedobacter heparinus
0.0854
-
 heparin isoform HepI, pH 7.4, 30°C Pedobacter heparinus
0.292
-
 heparin isoform HepIII, pH 7.4, 30°C Pedobacter heparinus

Organism

Organism UniProt Comment Textmining
Pedobacter heparinus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
heparin
-
 Pedobacter heparinus ?
-
 ?
additional information isoforms heparinase I and heparinase II can depolymerize heparin more efficiently than isoform heparinase III, respectively, but heparinase III is the best able to protect the anticoagulant activities of low molecular weight heparins. Heparinase III and heparinase I/II combinations are able to efficiently depolymerize heparin to low molecular weight heparins with higher anticoagulant activity than the low molecular weight heparins produced by the respective heparinase I and heparinase II. HepIII and HepI is the best combination for maintaining high anti-IIa activity at the same molecular weight value Pedobacter heparinus ?
-
 ?