KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0468 | - |
heparin | isoform HepII, pH 7.4, 30°C | Pedobacter heparinus | |
0.0854 | - |
heparin | isoform HepI, pH 7.4, 30°C | Pedobacter heparinus | |
0.292 | - |
heparin | isoform HepIII, pH 7.4, 30°C | Pedobacter heparinus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pedobacter heparinus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
heparin | - |
Pedobacter heparinus | ? | - |
? | |
additional information | isoforms heparinase I and heparinase II can depolymerize heparin more efficiently than isoform heparinase III, respectively, but heparinase III is the best able to protect the anticoagulant activities of low molecular weight heparins. Heparinase III and heparinase I/II combinations are able to efficiently depolymerize heparin to low molecular weight heparins with higher anticoagulant activity than the low molecular weight heparins produced by the respective heparinase I and heparinase II. HepIII and HepI is the best combination for maintaining high anti-IIa activity at the same molecular weight value | Pedobacter heparinus | ? | - |
? |