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Literature summary for 4.2.2.7 extracted from

  • Xiao, Z.; Zhao, W.; Yang, B.; Zhang, Z.; Guan, H.; Linhardt, R.J.
    Heparinase 1 selectivity for the 3,6-di-O-sulfo-2-deoxy-2-sulfamido-alpha-D-glucopyranose (1,4) 2-O-sulfo-alpha-L-idopyranosyluronic acid (GlcNS3S6S-IdoA2S) linkages (2011), Glycobiology, 21, 13-22.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression of heparinase I in Escherichia coli Pedobacter heparinus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Pedobacter heparinus heparinase 1 shows selectivity for 3,6-di-O-sulfo-2-deoxy-2-sulfamido-alpha-D-glucopyranose (1,4) 2-O-sulfo-alpha-L-idopyranosyluronic acid, GlcNS3S6S-IdoA2S, linkages, overview ?
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Organism

Organism UniProt Comment Textmining
Pedobacter heparinus
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Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information heparinase 1 shows selectivity for 3,6-di-O-sulfo-2-deoxy-2-sulfamido-alpha-D-glucopyranose (1,4) 2-O-sulfo-alpha-L-idopyranosyluronic acid, GlcNS3S6S-IdoA2S, linkages, overview Pedobacter heparinus ?
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?
additional information porcine intestinal mucosa heparin is partially depolymerized by recombinant heparinase 1 and then fractionated, leading to the isolation of 22 homogeneous oligosaccharides with sizes ranging from disaccharide to hexadecasaccharide. Product analysis by electrospray ionization-mass spectrometry and structure determination using one- and two-dimensional nuclear magnetic resonance spectroscopy at 600 MHz, detailed overview Pedobacter heparinus ?
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?

Synonyms

Synonyms Comment Organism
heparin lyase 1
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Pedobacter heparinus
heparinase I
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Pedobacter heparinus
HepI
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Pedobacter heparinus