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Literature summary for 4.2.2.5 extracted from
- Action of chondroitinases. III. Ionic strength effects and kinetics in the action of chondroitinase AC (1977), J. Biochem., 82, 429-436.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Cu2+ | - |
Paenarthrobacter aurescens |  |
| dermatan sulfate | - |
Paenarthrobacter aurescens | |
| Fe2+ | - |
Paenarthrobacter aurescens | |
| Pb2+ | - |
Paenarthrobacter aurescens | |
| Sn2+ | - |
Paenarthrobacter aurescens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | effect of temperature in the Km-value | Pedobacter heparinus | |
| additional information | - |
additional information | effect of temperature in the Km-value | Paenarthrobacter aurescens | |
| 0.1 | - |
chondroitin 4-sulfate | 20°C | Pedobacter heparinus | |
| 0.121 | - |
chondroitin 6-sulfate | 20°C | Pedobacter heparinus | |
| 0.215 | - |
chondroitin 6-sulfate | 20°C | Paenarthrobacter aurescens | |
| 0.217 | - |
hyaluronate | 20°C | Pedobacter heparinus | |
| 0.239 | - |
chondroitin | 20°C | Paenarthrobacter aurescens | |
| 0.239 | - |
hyaluronate | 20°C | Paenarthrobacter aurescens | |
| 0.273 | - |
chondroitin | 20°C | Pedobacter heparinus | |
| 0.376 | - |
chondroitin 4-sulfate | 20°C | Paenarthrobacter aurescens | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ba2+ | activates more effectively than univalent cations | Paenarthrobacter aurescens | |
| Ca2+ | activates more effectively than univalent cations | Paenarthrobacter aurescens | |
| Co2+ | activates more effectively than univalent cations | Paenarthrobacter aurescens | |
| K+ | activates | Paenarthrobacter aurescens | |
| Mg2+ | activates more effectively than univalent cations | Paenarthrobacter aurescens | |
| Na+ | activates | Paenarthrobacter aurescens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Paenarthrobacter aurescens | - |
- |
- |
| Pedobacter heparinus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| chondroitin | - |
Pedobacter heparinus | ? | - |
? | |
| chondroitin | - |
Paenarthrobacter aurescens | ? | - |
? | |
| hyaluronate | - |
Paenarthrobacter aurescens | ? | - |
? | |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | effect of temperature in the turnover number | Pedobacter heparinus | |
| additional information | - |
additional information | effect of temperature in the turnover number | Paenarthrobacter aurescens | |
| 308 | - |
chondroitin 4-sulfate | 20°C | Pedobacter heparinus | |
| 345 | - |
chondroitin 6-sulfate | 20°C | Pedobacter heparinus | |
| 403 | - |
chondroitin 4-sulfate | 20°C | Paenarthrobacter aurescens | |
| 522 | - |
chondroitin 6-sulfate | 20°C | Paenarthrobacter aurescens | |
| 570 | - |
hyaluronate | 20°C | Pedobacter heparinus | |
| 840 | - |
chondroitin | 20°C | Pedobacter heparinus | |
| 868 | - |
chondroitin | 20°C | Paenarthrobacter aurescens | |
| 1200 | - |
hyaluronate | 20°C | Paenarthrobacter aurescens | |
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