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Literature summary for 4.2.2.21 extracted from
- Preparation and purification of Flavobacterium heparinum chondroitinases AC and B by hydrophobic interaction chromatography (1999), Braz. J. Med. Biol. Res., 32, 545-550.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | not inhibitory: ammonium sulfate | Pedobacter heparinus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pedobacter heparinus | - |
isoform chondroitinase AC, upon growth on peptone with or without the inducer chondroitin sulfate, high specific activities for chondroitinases during the initial 6 h, which decreased thereafter. In contrast, in tryptic soy broth, high specific activities were obtained after 24 h growth in the presence of the inducer, generating large amounts of chondroitinase-rich extracts | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| isoform chondroitinase AC, cell disruption by ultrasound, under mild conditions, solubilization of most of enzyme activity | Pedobacter heparinus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| chondroitin sulfate | - |
Pedobacter heparinus | unsaturated sulfated chondroitin disaccharide | - |
? |  |
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