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Literature summary for 4.2.1.91 extracted from

  • Corea, O.R.; Bedgar, D.L.; Davin, L.B.; Lewis, N.G.
    The arogenate dehydratase gene family: towards understanding differential regulation of carbon flux through phenylalanine into primary versus secondary metabolic pathways (2012), Phytochemistry, 82, 22-37.
    View publication on PubMed
Search for more literature for 4.2.1.91

Protein Variants

Protein Variants Comment Organism
additional information homozygous T-DNA insertion lines are generated for five of the six ADT isozymes and used to generate double, triple, and quadruple knockout mutants in different combinations, regulation phenotypes,overview Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
 Arabidopsis thaliana 9507
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arogenate Arabidopsis thaliana
-
 L-phenylalanine + H2O + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 six isozymes encoded by genes adt1-adt6
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Arabidopsis thaliana
-
additional information L-Phe/Tyr and general amino acid pools development during weeks in tissues of isozyme knockout mutants compared to the wild-type enzyme, overview Arabidopsis thaliana
-
root
-
 Arabidopsis thaliana
-
stem
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arogenate
-
 Arabidopsis thaliana L-phenylalanine + H2O + CO2
-
 ?

Synonyms

Synonyms Comment Organism
AdT
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function the enzyme is required for biosynthesis of L-phenylalanine. Specific ADTs are differentially regulated so as to control Phe biosynthesis for protein synthesis versus its much more massive deployment for phenylpropanoid metabolism, overview Arabidopsis thaliana