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Literature summary for 4.2.1.88 extracted from

  • Veeraswamy, M.; Devi, N.A.; Kutty, R.K.; Rao, P.V.S.
    Conversion of (+/-)-synephrine into p-hydroxyphenylacetaldehyde by Arthrobacter synephrinum. A novel enzymic reaction (1976), Biochem. J., 159, 807-809.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.1.88

Activating Compound

Activating Compound Comment Organism Structure
2-mercaptoethanol enhances activity Arthrobacter synephrinum
glutathione enhances activity Arthrobacter synephrinum

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ absolute requirement for divalent cations, e.g. Mg2+ or Ca2+ Arthrobacter synephrinum
Mg2+ absolute requirement for divalent cations, e.g. Mg2+ or Ca2+ Arthrobacter synephrinum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(+/-)-synephrine Arthrobacter synephrinum (+/-)-synephrine metabolism 4-hydroxyphenylacetaldehyde + methylamine
-
 ?

Organism

Organism UniProt Comment Textmining
Arthrobacter synephrinum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Arthrobacter synephrinum

Reaction

Reaction Comment Organism Reaction ID
(R)-synephrine = (4-hydroxyphenyl)acetaldehyde + methylamine removal of H2O from (+/-)-synephrine produces a 2,3-enamine, which hydrolyzes to the products Arthrobacter synephrinum
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(+/-)-synephrine i.e. 1-(4-hydroxyphenyl)-2-(methylamino)ethanol, highly specific, removal of H2O from (+/-)-synephrine produces a 2,3-enamine, which hydrolyzes to the products, oxygen-independent reaction Arthrobacter synephrinum 4-hydroxyphenylacetaldehyde + methylamine
-
 ?
(+/-)-synephrine (+/-)-synephrine metabolism Arthrobacter synephrinum 4-hydroxyphenylacetaldehyde + methylamine
-
 ?
additional information not: tyramine, N-methyltyramine, N,N’-dimethyltyramine Arthrobacter synephrinum ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Arthrobacter synephrinum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 around Arthrobacter synephrinum