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Literature summary for 4.2.1.84 extracted from

  • Tauber, M.M.; Cavaco-Paulo, A.; Robra, K.; Gubitz, G.M.
    Nitrile hydratase and amidase from Rhodococcus rhodochrous hydrolyze acrylic fibers and granular polyacrylonitriles (2000), Appl. Environ. Microbiol., 66, 1634-1638.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.1.84

Activating Compound

Activating Compound Comment Organism Structure
dimethylformamide addition to increase the accessibility of nitrile groups at concentration no higher than 0.5% is beneficial for activity Rhodococcus rhodochrous

Application

Application Comment Organism
synthesis useful for modification of polyacrylonitrile fibers and granulates Rhodococcus rhodochrous

Organism

Organism UniProt Comment Textmining
Rhodococcus rhodochrous
-
-
-
Rhodococcus rhodochrous NCIMB 11216
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acrylamide + H2O
-
 Rhodococcus rhodochrous acrylonitrile
-
 ?
acrylamide + H2O
-
 Rhodococcus rhodochrous NCIMB 11216 acrylonitrile
-
 ?
acrylonitrile + H2O
-
 Rhodococcus rhodochrous 2-propenoic acid amide
-
 ?
acrylonitrile + H2O
-
 Rhodococcus rhodochrous NCIMB 11216 2-propenoic acid amide
-
 ?
propionitrile + H2O 10% of conversion in 24 h Rhodococcus rhodochrous propionic acid amide i.e. propionamide ?
propionitrile + H2O 10% of conversion in 24 h Rhodococcus rhodochrous NCIMB 11216 propionic acid amide i.e. propionamide ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
-
 Rhodococcus rhodochrous