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Literature summary for 4.2.1.47 extracted from

  • Sturla, L.; Etzioni, A.; Biso, A.; Zanardi, D.; De Flora, G.; Silengo, L.; De Flora, A.; Tonetti, M.
    Defective intracellular activity of GDP-D-mannose 4,6-dehydratase in leukocyte adhesion deficiency type II syndrome (1998), FEBS Lett., 429, 274-278.
    View publication on PubMed
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KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.003
-
 GDPmannose
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GDPmannose Homo sapiens synthesis of various glycoconjugates ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens O60547 human
-

Source Tissue

Source Tissue Comment Organism Textmining
lymphocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.7
-
-
 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-mannose
-
 Homo sapiens GDP-4-dehydro-6-deoxy-D-mannose + H2O
-
 ?
GDPmannose synthesis of various glycoconjugates Homo sapiens ?
-
 ?