Activating Compound | Comment | Organism | Structure |
---|---|---|---|
NADPH | activates | Escherichia coli | |
NADPH | activates | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Escherichia coli |
expression in Escherichia coli | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
GDP-L-fucose | - |
Escherichia coli | |
GDP-L-fucose | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.08 | - |
GDPmannose | - |
Homo sapiens | |
0.26 | - |
GDPmannose | - |
Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDPmannose | Escherichia coli | - |
? | - |
? | |
GDPmannose | Homo sapiens | synthesis of various glycoconjugates | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Homo sapiens | - |
human | - |
Purification (Comment) | Organism |
---|---|
- |
Escherichia coli |
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
colon | - |
Homo sapiens | - |
heart | - |
Homo sapiens | - |
kidney | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
additional information | including cultured cells | Homo sapiens | - |
pancreas | - |
Homo sapiens | - |
prostate gland | - |
Homo sapiens | - |
small intestine | - |
Homo sapiens | - |
thymus | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.11 | - |
- |
Homo sapiens |
0.73 | - |
- |
Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-mannose | - |
Escherichia coli | GDP-4-dehydro-6-deoxy-D-mannose + H2O | - |
? | |
GDP-mannose | - |
Homo sapiens | GDP-4-dehydro-6-deoxy-D-mannose + H2O | - |
? | |
GDPmannose | - |
Escherichia coli | ? | - |
? | |
GDPmannose | synthesis of various glycoconjugates | Homo sapiens | ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Escherichia coli |
37 | - |
assay at | Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.5 | 8 | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | strict requirement, cannot be substituted by NAD+ | Escherichia coli | |
NADP+ | strict requirement, cannot be substituted by NAD+ | Homo sapiens |