Literature summary for 4.2.1.24 extracted from

Nogueira, C.W.; Soares, F.A.; Nascimento, P.C.; Muller, D.; Rocha, J.B.
2,3-Dimercaptopropane-1-sulfonic acid and meso-2,3-dimercaptosuccinic acid increase mercury- and cadmium-induced inhibition of delta-aminolevulinate dehydratase (2003), Toxicology, 184, 85-95.

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Inhibitors

Inhibitors	Comment	Organism	Structure
2,3-dimercaptopropane-1-sulfonic acid	in presence of Hg2+ or Cd2+ the inhibitory potency increases, no change in inhibitory potency by inclusion of Pb2+, Zn2+ does not modify the inhibitory effect	Homo sapiens
Hg2+	inhibitory effect is increased by meso-2,3-dimercaptosuccinic acid, inhibition is prevented by dithiothreitol	Homo sapiens
meso-2,3-dimercaptosuccinic acid	in presence of Hg2+ or Cd2+ the inhibitory potency increases, Zn2+ does not modify the inhibitory effect	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Homo sapiens	-

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Release 2023.1 (January 2023)