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Literature summary for 4.2.1.22 extracted from

  • Shen, W.; McGath, M.K.; Evande, R.; Berkowitz, D.B.
    A continuous spectrophotometric assay for human cystathionine beta-synthase (2005), Anal. Biochem., 342, 103-110.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.2.1.22

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2
-
 L-serine pH 8.0, 37°C, reaction with cysteamine, continous UV assay Homo sapiens
2.2
-
 L-serine pH 8.0, 37°C, reaction with cysteamine, Mudd assay Homo sapiens
3.7
-
 L-homocysteine pH 8.0, 37°C Homo sapiens
4.9
-
 L-serine pH 8.0, 37°C, reaction with L-homocysteine Homo sapiens
5.6
-
 cysteamine pH 8.0, 37°C, UV assay Homo sapiens
6.6
-
 cysteamine pH 8.0, 37°C, Mudd assay Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 continous spectrometric assay for cystathionine beta-synthase Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-serine + cysteamine
-
 Homo sapiens L-thialysine
-
 ?
L-serine + L-homocysteine
-
 Homo sapiens cystathionine + H2O
-
 ?

Synonyms

Synonyms Comment Organism
hCBS
-
 Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.3
-
 L-serine pH 8.0, 37°C, reaction with cysteamine, continous UV assay Homo sapiens
2.5
-
 L-serine pH 8.0, 37°C, reaction with cysteamine, Mudd assay Homo sapiens
7.5
-
 L-serine pH 8.0, 37°C, reaction with L-homocysteine Homo sapiens