Literature summary for 4.2.1.20 extracted from

Axe, J.M.; Boehr, D.D.
Long-range interactions in the ? subunit of tryptophan synthase help to coordinate ligand binding, catalysis, and substrate channeling (2013), J. Mol. Biol., 425, 1527-1545.

Search for more literature for 4.2.1.20

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate	Salmonella enterica subsp. enterica serovar Typhimurium	-	L-tryptophan + D-glyceraldehyde 3-phosphate + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Salmonella enterica subsp. enterica serovar Typhimurium	P00929	alpha subunit	-

Purification (Commentary)

Purification (Comment)	Organism
Q-Sepharose column chromatography and gel filtration	Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate	-	Salmonella enterica subsp. enterica serovar Typhimurium	L-tryptophan + D-glyceraldehyde 3-phosphate + H2O	-	?

Synonyms

Synonyms	Comment	Organism
alphaTS	alpha-subunit of tryptophan synthase	Salmonella enterica subsp. enterica serovar Typhimurium

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)