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Literature summary for 4.2.1.20 extracted from

  • Phillips, R.S.; Miles, E.W.; Holtermann, G.; Goody, R.S.
    Hydrostatic pressure affects the conformational equilibrium of Salmonella typhimurium tryptophan synthase (2005), Biochemistry, 44, 7921-7928.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information Trp synthase exhibits low-activity (open) and high-activity (closed conformation). The open conformation is favored by high hydrostatic pressure. It is estimated that there are 35-47 more waters in the solvation shell of the open conformation than in that of the closed conformation Salmonella enterica subsp. enterica serovar Typhimurium

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium
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Synonyms

Synonyms Comment Organism
Trp synthase
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Salmonella enterica subsp. enterica serovar Typhimurium