Literature summary for 4.2.1.146 extracted from

Valkonen, M.; Penttilae, M.; Bencina, M.
Intracellular pH responses in the industrially important fungus Trichoderma reesei (2014), Fungal Genet. Biol., 70, 86-93 .

Search for more literature for 4.2.1.146

Cloned(Commentary)

Cloned (Comment)	Organism
gene lgd1, expression analysis in wild-type and mutant strain, introduction of pHluorin, called RaVC, for the analysis of intracellular pH, the RaVC gene is cloned into expression vector pMV119 using yeast recombinational cloning, and cytosolic localization	Trichoderma reesei

Protein Variants

Protein Variants	Comment	Organism
additional information	strain M106, derived from wild-type strain Rut-C30, accumulates L-galactonic acid from provided galacturonic acid due to a L-galactonate dehydratase deletion. Strain M106 maintains higher intracellular pH in the presence of D-galacturonic acid than its parental strain Rut-C30. The acidic external pH caused significant acidification of cytosol	Trichoderma reesei

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-galactonate	Trichoderma reesei	-	2-dehydro-3-deoxy-L-galactonate + H2O	-	?
L-galactonate	Trichoderma reesei Rut-C30	-	2-dehydro-3-deoxy-L-galactonate + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Trichoderma reesei	Q0QWS4	i.e. Hypocrea jecorina	-
Trichoderma reesei Rut-C30	Q0QWS4	i.e. Hypocrea jecorina	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-galactonate	-	Trichoderma reesei	2-dehydro-3-deoxy-L-galactonate + H2O	-	?
L-galactonate	-	Trichoderma reesei Rut-C30	2-dehydro-3-deoxy-L-galactonate + H2O	-	?

Synonyms

Synonyms	Comment	Organism
LGD1	-	Trichoderma reesei

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)