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Literature summary for 4.2.1.125 extracted from

  • Lee, M.H.; Han, J.Y.; Kim, H.J.; Kim, Y.S.; Huh, G.H.; Choi, Y.E.
    Dammarenediol-II production confers TMV tolerance in transgenic tobacco expressing Panax ginseng dammarenediol-II synthase (2012), Plant Cell Physiol., 53, 173-182.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
gene PgDDS, functional expression in Nicotiana tabacum cv. Xanthi leaves using Agrobacterium strain GV3101, the heterologous expression confers resistance to Tobacco mosaic virus. Expression profile of PgDDS trangenic tobacco plants, overview. Production of dammarenediol-II in transgenic tobacco stimulates the expression of tobacco pathogenesis-related genes (PR1 and PR2) under both virus-untreated and -treated conditions Panax ginseng

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O Panax ginseng dammarenediol-II is a ginsenoside precursor dammarenediol II
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 ?

Organism

Organism UniProt Comment Textmining
Panax ginseng Q08IT1 gene PgDDS
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Source Tissue

Source Tissue Comment Organism Textmining
root
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 Panax ginseng
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
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 Panax ginseng dammarenediol II GC-MS product analysis ?
(3S)-2,3-epoxy-2,3-dihydrosqualene + H2O dammarenediol-II is a ginsenoside precursor Panax ginseng dammarenediol II
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 ?

Synonyms

Synonyms Comment Organism
dammarenediol-II synthase
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 Panax ginseng

General Information

General Information Comment Organism
metabolism the enzyme catalyzes the first step in the synthesis of dammarane-type ginsenoside, the cyclization of 2,3-oxidosqualene to dammarenediol-II, overview Panax ginseng