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BRENDA support

Literature summary for extracted from

  • Rodriguez, M.; Wedd, A.G.; Scopes, R.K.
    6-Phosphogluconate dehydratase from Zymomonas mobilis: an iron-sulfur-manganese enzyme (1996), Biochem. Mol. Biol. Int., 39, 783-789.
    View publication on PubMed

General Stability

General Stability Organism
alpha-glycerophosphate stabilizes Zymomonas mobilis
Mn2+ stabilizes Zymomonas mobilis


Inhibitors Comment Organism Structure
Zymomonas mobilis


Metals/Ions Comment Organism Structure
Iron contains 4 Fe per 63000 Da subunit Zymomonas mobilis
Iron active site includes an Fe4S4 cluster Zymomonas mobilis
Mn2+ the enzyme contains one Mn2+ per subunit, which is essential for activity, may be involved in binding of the substrate Zymomonas mobilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-phospho-D-gluconate Zymomonas mobilis key enzyme in the Entner-Doudoroff pathway ?


Organism UniProt Comment Textmining
Zymomonas mobilis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Zymomonas mobilis 6-phospho-2-dehydro-3-deoxy-D-gluconate + H2O
6-phospho-D-gluconate key enzyme in the Entner-Doudoroff pathway Zymomonas mobilis ?