Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-hydroxy-2-nonenal | - |
Homo sapiens | |
4-hydroxy-2-nonenal | - |
Sus scrofa | |
acrolein | - |
Homo sapiens | |
acrolein | - |
Sus scrofa | |
methylglyoxal | - |
Homo sapiens | |
methylglyoxal | - |
Sus scrofa | |
additional information | the muscle-specific enolase is used as a model enzyme for inhibition analysis by acrolein, 4-hydroxy-2-nonenal, and trans-2-nonenal, incubation for 1-24 h at 25°C, 37°C, and 45°C, overview. The compounds show inhibition effectivity in the following descending order: inhibition degree of enolase activity occurred in following order: 4-hydroxy-2-nonenal, acrolein, methylglyoxal, trans-2-nonenal, overview | Homo sapiens | |
additional information | the muscle-specific enolase is used as a model enzyme for inhibition analysis by acrolein, 4-hydroxy-2-nonenal, and trans-2-nonenal, incubation for 1-24 h at 25°C, 37°C, and 45°C, overview. The compounds show inhibition effectivity in the following descending order: inhibition degree of enolase activity occurred in following order: 4-hydroxy-2-nonenal, acrolein, methylglyoxal, trans-2-nonenal, overview | Sus scrofa | |
trans-2-nonenal | - |
Homo sapiens | |
trans-2-nonenal | - |
Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native enzyme from muscle by ammonium sulfate fractionation and ion exchange chromatography | Homo sapiens |
native enzyme from muscle by ammonium sulfate fractionation and ion exchange chromatography | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skeletal muscle | muscle-specific enolase | Homo sapiens | - |
skeletal muscle | muscle-specific enolase | Sus scrofa | - |
Synonyms | Comment | Organism |
---|---|---|
beta-enolase | - |
Homo sapiens |
beta-enolase | - |
Sus scrofa |
enolase | - |
Homo sapiens |
enolase | - |
Sus scrofa |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
22 | - |
assay at room temperature | Homo sapiens |
22 | - |
assay at room temperature | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.8 | - |
assay at | Homo sapiens |
6.8 | - |
assay at | Sus scrofa |
General Information | Comment | Organism |
---|---|---|
additional information | the human muscle-specific enolase is less susceptible to inactivation by reactive aldehydes than the pig enzyme | Homo sapiens |
additional information | the human muscle-specific enolase is less susceptible to inactivation by reactive aldehydes than the pig enzyme | Sus scrofa |