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Literature summary for 4.2.1.11 extracted from

  • Wygrecka, M.; Marsh, L.M.; Morty, R.E.; Henneke, I.; Guenther, A.; Lohmeyer, J.; Markart, P.; Preissner, K.T.
    Enolase-1 promotes plasminogen-mediated recruitment of monocytes to the acutely inflamed lung (2009), Blood, 113, 5588-5598.
    View publication on PubMed
Search for more literature for 4.2.1.11

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-phospho-D-glycerate Homo sapiens
-
 phosphoenolpyruvate + H2O
-
 r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
monocyte
-
 Homo sapiens
-
U-937 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phospho-D-glycerate
-
 Homo sapiens phosphoenolpyruvate + H2O
-
 r

Synonyms

Synonyms Comment Organism
ENO-1
-
 Homo sapiens
enolase-1
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens lipopolysaccharide rapidly up-regulates ENO-1 cell-surface expression up

General Information

General Information Comment Organism
physiological function ENO-1 binds plasminogen at the cell surface, enhancing local plasmin production, overexpression of ENO-1 in U937 cells increases their migratory and matrix-penetrating capacity Homo sapiens