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Literature summary for 4.2.1.11 extracted from

  • Kaufmann, M.; Batholmes, P.
    Purification, characterization and inhibition by fluoride of enolase from Streptococcus mutans DSM 320523 (1992), Caries Res., 26, 110-116.
    View publication on PubMed
Search for more literature for 4.2.1.11

Inhibitors

Inhibitors Comment Organism Structure
F- noncompetitive inhibition below 10 mM, competitive above 10 mM Streptococcus mutans
additional information inhibition of enolase by fluoride in combination with phosphate can influence glycolysis and so reduce acid production of even growth rate, thereby leading to potential anticariogenic effects Streptococcus mutans
Na2PO3F
-
 Streptococcus mutans

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.44
-
 2-phospho-D-glycerate in presence of 1 mM Mg2+ Streptococcus mutans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
 8 * 45000, SDS-PAGE Streptococcus mutans
350000
-
 equilibrium sedimentation Streptococcus mutans

Organism

Organism UniProt Comment Textmining
Streptococcus mutans
-
 DSM 320523
-

Purification (Commentary)

Purification (Comment) Organism
-
 Streptococcus mutans

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-phospho-D-glycerate
-
 Streptococcus mutans phosphoenolpyruvate
-
 ?
2-phospho-D-glycerate
-
 Streptococcus mutans phosphoenolpyruvate + H2O
-
 ?

Subunits

Subunits Comment Organism
octamer 8 * 45000, SDS-PAGE Streptococcus mutans