Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(1R,4R,5R)-3-(2-carboxy-vinyl)-1,4,5-trihydroxy-cyclohex-2-enecarboxylic acid | - |
Mycobacterium tuberculosis | |
(1R,4R,5R)-3-(2-carboxy-vinyl)-1,4,5-trihydroxy-cyclohex-2-enecarboxylic acid | - |
Streptomyces coelicolor | |
(1R,4R,5R)-3-(tert-butylcarbamoyl)-1,4,5-trihydroxycyclohex-2-enecarboxylic acid | - |
Mycobacterium tuberculosis | |
(1R,4R,5R)-3-(tert-butylcarbamoyl)-1,4,5-trihydroxycyclohex-2-enecarboxylic acid | - |
Streptomyces coelicolor | |
(3R,5R,6R)-3,5,6-trihydroxycyclohex-1-ene-1,3-dicarboxylic acid | - |
Mycobacterium tuberculosis | |
(3R,5R,6R)-3,5,6-trihydroxycyclohex-1-ene-1,3-dicarboxylic acid | - |
Streptomyces coelicolor | |
(3R,5R,6R)-3-carbamoyl-3,5,6-trihydroxycyclohex-1-enecarboxylic acid | - |
Mycobacterium tuberculosis | |
(3R,5R,6R)-3-carbamoyl-3,5,6-trihydroxycyclohex-1-enecarboxylic acid | - |
Streptomyces coelicolor | |
3-hydroxy-cyclohex-1-ene-1,3-dicarboxylic acid | - |
Salmonella enterica subsp. enterica serovar Typhi | |
3-hydroxy-cyclohex-1-ene-1,3-dicarboxylic acid | - |
Streptomyces coelicolor | |
4-hydroxy-2-hydroxymethyl-4-methyl-pent-2-enedioic acid | - |
Salmonella enterica subsp. enterica serovar Typhi | |
4-hydroxy-2-hydroxymethyl-4-methyl-pent-2-enedioic acid | - |
Streptomyces coelicolor | |
4-hydroxy-4-methyl-pent-2-enedioic acid | - |
Salmonella enterica subsp. enterica serovar Typhi | |
4-hydroxy-4-methyl-pent-2-enedioic acid | - |
Streptomyces coelicolor |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Salmonella enterica subsp. enterica serovar Typhi | - |
- |
- |
Streptomyces coelicolor | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
Type I dehydroquinase | - |
Salmonella enterica subsp. enterica serovar Typhi |
Type II dehydroquinase | - |
Mycobacterium tuberculosis |
Type II dehydroquinase | - |
Streptomyces coelicolor |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000032 | - |
(3R,5R,6R)-3,5,6-trihydroxycyclohex-1-ene-1,3-dicarboxylic acid | pH 7.0 | Streptomyces coelicolor | |
0.00024 | - |
(3R,5R,6R)-3-carbamoyl-3,5,6-trihydroxycyclohex-1-enecarboxylic acid | pH 7.0 | Streptomyces coelicolor | |
0.00094 | - |
(3R,5R,6R)-3,5,6-trihydroxycyclohex-1-ene-1,3-dicarboxylic acid | pH 7.0 | Mycobacterium tuberculosis | |
0.016 | - |
(3R,5R,6R)-3-carbamoyl-3,5,6-trihydroxycyclohex-1-enecarboxylic acid | pH 7.0 | Mycobacterium tuberculosis | |
0.025 | - |
(1R,4R,5R)-3-(2-carboxy-vinyl)-1,4,5-trihydroxy-cyclohex-2-enecarboxylic acid | pH 7.0 | Streptomyces coelicolor | |
0.027 | - |
(1R,4R,5R)-3-(tert-butylcarbamoyl)-1,4,5-trihydroxycyclohex-2-enecarboxylic acid | pH 7.0 | Mycobacterium tuberculosis | |
0.029 | - |
(1R,4R,5R)-3-(tert-butylcarbamoyl)-1,4,5-trihydroxycyclohex-2-enecarboxylic acid | pH 7.0 | Streptomyces coelicolor | |
0.105 | - |
(1R,4R,5R)-3-(2-carboxy-vinyl)-1,4,5-trihydroxy-cyclohex-2-enecarboxylic acid | pH 7.0 | Mycobacterium tuberculosis | |
0.47 | - |
4-hydroxy-4-methyl-pent-2-enedioic acid | pH 7.0 | Streptomyces coelicolor | |
0.65 | - |
4-hydroxy-2-hydroxymethyl-4-methyl-pent-2-enedioic acid | pH 7.0 | Salmonella enterica subsp. enterica serovar Typhi | |
0.76 | - |
3-hydroxy-cyclohex-1-ene-1,3-dicarboxylic acid | pH 7.0 | Streptomyces coelicolor | |
0.99 | - |
4-hydroxy-4-methyl-pent-2-enedioic acid | pH 7.0 | Salmonella enterica subsp. enterica serovar Typhi | |
1 | - |
4-hydroxy-2-hydroxymethyl-4-methyl-pent-2-enedioic acid | pH 7.0 | Streptomyces coelicolor | |
1.7 | - |
3-hydroxy-cyclohex-1-ene-1,3-dicarboxylic acid | pH 7.0 | Salmonella enterica subsp. enterica serovar Typhi |