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Literature summary for 4.2.1.10 extracted from

  • Frederickson, M.; Parker, E.J.; Hawkins, A.R.; Coggins, J.R.; Abell, C.
    Selective inhibition of type II dehydroquinases (1999), J. Org. Chem., 64, 2612-2613.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
1,3,4-trihydroxy-5-hydroxyiminocyclohexanecarboxylic acid
-
Aspergillus nidulans
1,3,4-trihydroxy-5-hydroxyiminocyclohexanecarboxylic acid
-
Mycobacterium tuberculosis
1,3,4-trihydroxy-5-hydroxyiminocyclohexanecarboxylic acid poor inhibition Salmonella enterica subsp. enterica serovar Typhi
1,3,4-trihydroxy-5-hydroxyiminocyclohexanecarboxylic acid
-
Streptomyces coelicolor
1,3,4-trihydroxy-5-oxocyclohexanecarboxylic acid
-
Aspergillus nidulans
1,3,4-trihydroxy-5-oxocyclohexanecarboxylic acid
-
Mycobacterium tuberculosis
1,3,4-trihydroxy-5-oxocyclohexanecarboxylic acid poor inhibition Salmonella enterica subsp. enterica serovar Typhi
1,3,4-trihydroxy-5-oxocyclohexanecarboxylic acid
-
Streptomyces coelicolor
1,3,4-trihydroxycyclohexanecarboxylic acid
-
Aspergillus nidulans
1,3,4-trihydroxycyclohexanecarboxylic acid
-
Mycobacterium tuberculosis
1,3,4-trihydroxycyclohexanecarboxylic acid poor inhibition Salmonella enterica subsp. enterica serovar Typhi
1,3,4-trihydroxycyclohexanecarboxylic acid
-
Streptomyces coelicolor
1,4,5-trihydroxycyclohex-2-enecarboxylic acid
-
Aspergillus nidulans
1,4,5-trihydroxycyclohex-2-enecarboxylic acid
-
Mycobacterium tuberculosis
1,4,5-trihydroxycyclohex-2-enecarboxylic acid poor inhibition Salmonella enterica subsp. enterica serovar Typhi
1,4,5-trihydroxycyclohex-2-enecarboxylic acid
-
Streptomyces coelicolor
2,3-anhydroquinic acid
-
Aspergillus nidulans
2,3-anhydroquinic acid
-
Mycobacterium tuberculosis
2,3-anhydroquinic acid poor inhibition Salmonella enterica subsp. enterica serovar Typhi
2,3-anhydroquinic acid
-
Streptomyces coelicolor
3-deoxyquinic acid
-
Aspergillus nidulans
3-deoxyquinic acid
-
Mycobacterium tuberculosis
3-deoxyquinic acid poor inhibition Salmonella enterica subsp. enterica serovar Typhi
3-deoxyquinic acid
-
Streptomyces coelicolor

Organism

Organism UniProt Comment Textmining
Aspergillus nidulans
-
type II dehydroquinase
-
Mycobacterium tuberculosis
-
dehydroquinase type II
-
Salmonella enterica subsp. enterica serovar Typhi
-
-
-
Salmonella enterica subsp. enterica serovar Typhi
-
dehydroquinase type I
-
Streptomyces coelicolor
-
dehydroquinase type II
-