Any feedback?
Literature summary for 4.2.1.1 extracted from
- Functional characterization of mutants affected in the carbonic anhydrase domain of the respiratory complex I in Arabidopsis thaliana (2015), Plant J., 83, 831-844 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| Arabidopsis thaliana plant transformation for expression of mutant enzymes via Agrobacterium tumefaciens strain GV3101 | Arabidopsis thaliana |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | mutant phenotypes, overview | Arabidopsis thaliana |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Arabidopsis thaliana | 5739 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | required, metalloenzyme | Arabidopsis thaliana |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| H2CO3 | Arabidopsis thaliana | - |
CO2 + H2O | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | Q9C6B3 | - |
- |
| Arabidopsis thaliana | Q9FMV1 | - |
- |
| Arabidopsis thaliana | Q9FWR5 | - |
- |
| Arabidopsis thaliana | Q9SMN1 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell suspension culture | - |
Arabidopsis thaliana | - |
| rosette leaf | - |
Arabidopsis thaliana | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| H2CO3 | - |
Arabidopsis thaliana | CO2 + H2O | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AtCA1 | - |
Arabidopsis thaliana |
| AtCA2 | - |
Arabidopsis thaliana |
| AtCAL1 | - |
Arabidopsis thaliana |
| AtCAL2 | - |
Arabidopsis thaliana |
| gamma carbonic anhydrase 1 | - |
Arabidopsis thaliana |
| gamma carbonic anhydrase 2 | - |
Arabidopsis thaliana |
| gamma carbonic anhydrase-like 1 | - |
Arabidopsis thaliana |
| gamma carbonic anhydrase-like 2 | - |
Arabidopsis thaliana |
| gamma-CA1 | - |
Arabidopsis thaliana |
| gamma-CA2 | - |
Arabidopsis thaliana |
| gamma-CAL1 | - |
Arabidopsis thaliana |
| gamma-CAL2 | - |
Arabidopsis thaliana |
| gamma-carbonic anhydrase | - |
Arabidopsis thaliana |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Arabidopsis thaliana | transcript levels of specific CA subunits depend on the CO2 level in air | additional information |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | Arabidopsis thaliana mutants defective in two CA subunits show an altered photorespiratory phenotype. Mutants grown in ambient air show growth retardation compared to wild-type plants, a feature that is reversed by cultivating plants in a high-CO2 atmosphere. Under photorespiratory conditions, carbon assimilation is diminished and glycine accumulates, suggesting an imbalance with respect to photorespiration. Additionally, transcript levels of specific CA subunits are reduced in plants grown under non-photorespiratory conditions, leaves of ca2cal1 and ca2cal2 double mutants exhibited increased ROS levels. Mutants ca2cal1 and ca2cal2 show growth retardation in normal air. Mutant phenotypes, overview | Arabidopsis thaliana |
| malfunction | Arabidopsis thaliana mutants defective in two CA subunits show an altered photorespiratory phenotype. Mutants grown in ambient air show growth retardation compared to wild-type plants, a feature that is reversed by cultivating plants in a high-CO2 atmosphere. Under photorespiratory conditions, carbon assimilation is diminished and glycine accumulates, suggesting an imbalance with respect to photorespiration. Additionally, transcript levels of specific CA subunits are reduced in plants grown under non-photorespiratory conditions. Mutant phenotypes, overview | Arabidopsis thaliana |
| physiological function | the NADH-ubiquinone oxidoreductase complex (complex I, EC 1.6.5.3) is the main entrance site of electrons into the respiratory chain. In a variety of eukaryotic organisms, except animals and fungi (Opisthokonta), it contains an extra domain comprising trimers of putative gamma-carbonic anhydrases, named the CA domain, which has been proposed to be essential for assembly of complex I. The CA domain of plant complex I contributes to sustaining efficient photosynthesis under ambient (photorespiratory) conditions. The CA protein domain contains at least two different gamma-CA proteins, CA1 (At1g19580) and CA2 (At1g47260), which show conserved active-site regions, and two less well-conserved gamma-CA-like proteins, CAL1 (At5g63510) and CAL2 (At3g48680), containing non-conservative replacements of putatively important amino acids | Arabidopsis thaliana |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
