KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetic and thermodynamic analysis, molecular modelling, overview | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | required, metalloenzyme, molecular dynamics simulations in catalysis. Active site residues correspond to His94, His96, His119 belonging to the inner coordination shell of the metal ion and Glu106, Thr199, Thr200 belonging to the outer one | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
H2CO3 | Homo sapiens | - |
CO2 + H2O | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P00918 | - |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
H2CO3 = CO2 + H2O | reaction mechanism, analysis of the restoring step of the carbonic anhydrase catalytic cycle for natural and promiscuous substrates, natural HCO3-x02and promiscuous H2NCOHN- products, catalytic reaction mechanism, NPT molecular dynamics simulations, overview | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
H2CO3 | - |
Homo sapiens | CO2 + H2O | - |
r |
Synonyms | Comment | Organism |
---|---|---|
hCAII | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
additional information | enzyme structure, catalytic mechanism, and molecular dynamics simulations | Homo sapiens |