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Literature summary for 4.2.1.1 extracted from
- Activity and distribution of intracellular carbonic anhydrase II and their effects on the transport activity of anion exchanger AE1/SLC4A1 (2013), J. Physiol., 591, 4963-4982.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| coexpressed in tsA201 cells expressing heterologous fluorescent fusion proteins CAII-CyPet and YPet-AE1 | Homo sapiens |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| V143Y | inactive mutant | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CAII | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | a theoretical model predicts that homogeneous cytoplasmic distribution of CAII is more favourable for cellular transport of HCO3- and CO2 than is association of CAII with the cytoplasmic surface of the plasma membrane. Physiological interference with anion exchanger AE1 could not be demonstrated | Homo sapiens |
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Release 2023.1 (January 2023)
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