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Literature summary for 4.2.1.1 extracted from

  • Brzozowski, Z.; Slawinski, J.; Saczewski, F.; Innocenti, A.; Supuran, C.T.
    Carbonic anhydrase inhibitors: synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides (2010), Eur. J. Med. Chem., 45, 2396-2404.
    View publication on PubMed
Search for more literature for 4.2.1.1

Inhibitors

Inhibitors Comment Organism Structure
4,4'-thiodipyridine-3-sulfonamide
-
 Homo sapiens
4-(1,3,4-thiadiazol-2-ylthio)pyridine-3-sulfonamide
-
 Homo sapiens
4-(1-methyl-5-tetrazolylthio)pyridine-3-sulfonamide
-
 Homo sapiens
4-(2-methyl-8-quinolinoxy)-3-pyridinesulfonamide
-
 Homo sapiens
4-(2-propynylthio)pyridine-3-sulfonamide
-
 Homo sapiens
4-(4-cyanophenoxy)-3-pyridinesulfonamide
-
 Homo sapiens
4-(4-fluorophenoxy)-3-pyridinesulfonamide
-
 Homo sapiens
4-(5-methyl-2-pyrazolino)-3-pyridinesulfonamide
-
 Homo sapiens
4-(6-nitrobenzothiazol-2-ylthio)pyridine-3-sulfonamide
-
 Homo sapiens
4-(allylamino)-3-pyridinesulfonamide
-
 Homo sapiens
4-(carbamoylmethylthio)pyridine-3-sulfonamide
-
 Homo sapiens
4-(cyanomethylthio)pyridine-3-sulfonamide
-
 Homo sapiens
4-(methylhydrazino)-3-pyridinesulfonamide
-
 Homo sapiens
4-(N-oxide-2-pyridylthio)pyridine-3-sulfonamide
-
 Homo sapiens
4-(quinolinoxy)-3-pyridinesulfonamide
-
 Homo sapiens
4-benzythiopyridine-3-sulfonamide
-
 Homo sapiens
4-ethoxy-3-pyridinesulfonamide
-
 Homo sapiens
4-hydrazino-3-pyridinesulfonamide
-
 Homo sapiens
4-methoxy-3-pyridinesulfonamide
-
 Homo sapiens
4-methylthiopyridine-3-sulfonamide
-
 Homo sapiens
4-[2-(4-sulfamoylphenyl)ethylamino]-3-pyridinosulfonamide
-
 Homo sapiens
4-[N'-(1,1-dioxopyrido[4,3-e]-1,4,2-dithiazin-3-yl)hydrazino]-3-pyridinesulfonamide
-
 Homo sapiens
4-[N'-(6-chloro-7-cyano-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide
-
 Homo sapiens
4-[N'-(6-chloro-7-methyl-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide
-
 Homo sapiens
acetazolamide
-
 Homo sapiens
dichlorophenamide
-
 Homo sapiens
ethoxzolamide
-
 Homo sapiens
indisulam
-
 Homo sapiens
methazolamide
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol isoforms CA I and CA II Homo sapiens 5829
-
membrane isoforms CA XIV, CA IX and CA XII are transmembrane proteins Homo sapiens 16020
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO2 + H2O
-
 Homo sapiens H2CO3
-
 r

Synonyms

Synonyms Comment Organism
CA I isoform Homo sapiens
CA II isoform Homo sapiens
CA IX isoform Homo sapiens
CA XII isoform Homo sapiens
CA XIV isoform Homo sapiens
carbonic anhydrase
-
 Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00000216
-
 4-(6-nitrobenzothiazol-2-ylthio)pyridine-3-sulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000034
-
 methazolamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000034
-
 indisulam isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000034
-
 4-[N'-(6-chloro-7-cyano-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000042
-
 4-(1-methyl-5-tetrazolylthio)pyridine-3-sulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000046
-
 4-(1-methyl-5-tetrazolylthio)pyridine-3-sulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000046
-
 4-[N'-(1,1-dioxopyrido[4,3-e]-1,4,2-dithiazin-3-yl)hydrazino]-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000047
-
 4,4'-thiodipyridine-3-sulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000049
-
 4-hydrazino-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000051
-
 4-(1,3,4-thiadiazol-2-ylthio)pyridine-3-sulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000057
-
 4-methoxy-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000057
-
 acetazolamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000058
-
 4-[N'-(6-chloro-7-methyl-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazyno]-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000058
-
 4-methoxy-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000059
-
 4-ethoxy-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000063
-
 4-(2-propynylthio)pyridine-3-sulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000063
-
 4-(4-cyanophenoxy)-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000065
-
 4-benzythiopyridine-3-sulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000067
-
 4-(2-methyl-8-quinolinoxy)-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000067
-
 4-methylthiopyridine-3-sulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000068
-
 4-(quinolinoxy)-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000069
-
 4-(4-fluorophenoxy)-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000072
-
 4-[N'-(6-chloro-7-cyano-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000072
-
 4-(4-cyanophenoxy)-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000075
-
 4-[2-(4-sulfamoylphenyl)ethylamino]-3-pyridinosulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000075
-
 4-(N-oxide-2-pyridylthio)pyridine-3-sulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000077
-
 4-(1,3,4-thiadiazol-2-ylthio)pyridine-3-sulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000078
-
 4-(5-methyl-2-pyrazolino)-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000079
-
 4-(4-fluorophenoxy)-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000008
-
 ethoxzolamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000081
-
 4-[N'-(6-chloro-7-methyl-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000089
-
 4-(methylhydrazino)-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000091
-
 4-(quinolinoxy)-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000096
-
 4-(6-nitrobenzothiazol-2-ylthio)pyridine-3-sulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000099
-
 4-benzythiopyridine-3-sulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000101
-
 4-hydrazino-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000117
-
 4-(cyanomethylthio)pyridine-3-sulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000118
-
 4-(carbamoylmethylthio)pyridine-3-sulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000012
-
 acetazolamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000012
-
 4-(allylamino)-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000138
-
 4-(N-oxide-2-pyridylthio)pyridine-3-sulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000014
-
 methazolamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000015
-
 indisulam isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000151
-
 4-[2-(4-sulfamoylphenyl)ethylamino]-3-pyridinosulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000155
-
 4-(cyanomethylthio)pyridine-3-sulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000156
-
 4-(2-propynylthio)pyridine-3-sulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000157
-
 4-(5-methyl-2-pyrazolino)-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000158
-
 4-(methylhydrazino)-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000159
-
 4-(carbamoylmethylthio)pyridine-3-sulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000161
-
 4-[N'-(1,1-dioxopyrido[4,3-e]-1,4,2-dithiazin-3-yl)hydrazino]-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000169
-
 4-(allylamino)-3-pyridinesulfonamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000022
-
 ethoxzolamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000024
-
 indisulam isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000025
-
 ethoxzolamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000025
-
 acetazolamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000025
-
 ethoxzolamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000027
-
 methazolamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000304
-
 4-benzythiopyridine-3-sulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000031
-
 indisulam isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000034
-
 ethoxzolamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000038
-
 dichlorophenamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000401
-
 4-methylthiopyridine-3-sulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000041
-
 acetazolamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000043
-
 methazolamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000458
-
 4-(1-methyl-5-tetrazolylthio)pyridine-3-sulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000461
-
 4-[N'-(6-chloro-7-methyl-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazyno]-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000047
-
 4-methylthiopyridine-3-sulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000473
-
 4,4'-thiodipyridine-3-sulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00005
-
 dichlorophenamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00005
-
 dichlorophenamide isoform CA XII, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000509
-
 4-[N'-(6-chloro-7-methyl-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazyno]-3-pyridinesulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000052
-
 4-[2-(4-sulfamoylphenyl)ethylamino]-3-pyridinosulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000522
-
 4-ethoxy-3-pyridinesulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000564
-
 4-(2-propynylthio)pyridine-3-sulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000569
-
 4-(1,3,4-thiadiazol-2-ylthio)pyridine-3-sulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000597
-
 4-(quinolinoxy)-3-pyridinesulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000065
-
 4,4'-thiodipyridine-3-sulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000682
-
 4-benzythiopyridine-3-sulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00007
-
 4-(2-methyl-8-quinolinoxy)-3-pyridinesulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000767
-
 4-ethoxy-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000078
-
 4-[N'-(6-chloro-7-cyano-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000804
-
 4-(2-methyl-8-quinolinoxy)-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000837
-
 4-[N'-(1,1-dioxopyrido[4,3-e]-1,4,2-dithiazin-3-yl)hydrazino]-3-pyridinesulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000845
-
 4-(N-oxide-2-pyridylthio)pyridine-3-sulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000856
-
 4-hydrazino-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000872
-
 4-(methylhydrazino)-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000883
-
 4-[N'-(6-chloro-7-cyano-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000911
-
 4-(cyanomethylthio)pyridine-3-sulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000923
-
 4-[N'-(6-chloro-7-cyano-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazino]-3-pyridinesulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000934
-
 4-hydrazino-3-pyridinesulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00009384
-
 4-methoxy-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000944
-
 4-(4-fluorophenoxy)-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000945
-
 4-(4-cyanophenoxy)-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000948
-
 4-(6-nitrobenzothiazol-2-ylthio)pyridine-3-sulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0000957
-
 4-(methylhydrazino)-3-pyridinesulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000101
-
 4-[N'-(6-chloro-7-methyl-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazyno]-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000104
-
 indisulam isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000105
-
 4-(quinolinoxy)-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000108
-
 4-(2-propynylthio)pyridine-3-sulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000117
-
 4-[N'-(1,1-dioxopyrido[4,3-e]-1,4,2-dithiazin-3-yl)hydrazino]-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000131
-
 4-(carbamoylmethylthio)pyridine-3-sulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000133
-
 4-(allylamino)-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00014
-
 4-(5-methyl-2-pyrazolino)-3-pyridinesulfonamide isoform CA II, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00014
-
 4-(cyanomethylthio)pyridine-3-sulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000142
-
 4-(carbamoylmethylthio)pyridine-3-sulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000143
-
 4-(allylamino)-3-pyridinesulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000149
-
 4-[2-(4-sulfamoylphenyl)ethylamino]-3-pyridinosulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000152
-
 4-(5-methyl-2-pyrazolino)-3-pyridinesulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00016
-
 4,4'-thiodipyridine-3-sulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0003
-
 4-ethoxy-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00031
-
 acetazolamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000313
-
 4-(2-methyl-8-quinolinoxy)-3-pyridinesulfonamide isoform CA IX, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000345
-
 dichlorophenamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.000562
-
 4-(methylhydrazino)-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00078
-
 methazolamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0012
-
 dichlorophenamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00152
-
 4-[2-(4-sulfamoylphenyl)ethylamino]-3-pyridinosulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0061
-
 4-ethoxy-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00653
-
 4-(1-methyl-5-tetrazolylthio)pyridine-3-sulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00664
-
 4-(4-cyanophenoxy)-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00667
-
 4-(1,3,4-thiadiazol-2-ylthio)pyridine-3-sulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00734
-
 4-methoxy-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00762
-
 4-(N-oxide-2-pyridylthio)pyridine-3-sulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00791
-
 4-hydrazino-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00832
-
 4-(2-propynylthio)pyridine-3-sulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00884
-
 4-(6-nitrobenzothiazol-2-ylthio)pyridine-3-sulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00886
-
 4-(allylamino)-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0089
-
 4-[N'-(1,1-dioxopyrido[4,3-e]-1,4,2-dithiazin-3-yl)hydrazino]-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00903
-
 4-methylthiopyridine-3-sulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00909
-
 4-benzythiopyridine-3-sulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00916
-
 4-(4-fluorophenoxy)-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00951
-
 4-(carbamoylmethylthio)pyridine-3-sulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.00983
-
 4-methylthiopyridine-3-sulfonamide isoform CA XIV, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.0103
-
 4-(5-methyl-2-pyrazolino)-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.01032
-
 4-(quinolinoxy)-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.01032
-
 4-(2-methyl-8-quinolinoxy)-3-pyridinesulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.01117
-
 4,4'-thiodipyridine-3-sulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens
0.01171
-
 4-(cyanomethylthio)pyridine-3-sulfonamide isoform CA I, in 10 mM HEPES (pH 7.5), 0.1 M Na2SO4, at 22°C Homo sapiens