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Literature summary for 4.2.1.1 extracted from
- The effect of ethanol on erythrocyte carbonic anhydrase isoenzymes activity: an in vitro and in vivo study (2008), J. Enzyme Inhib. Med. Chem., 23, 266-270.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ethanol | - |
Homo sapiens |  |
| ethanol | carbonic anhydrase activity is significantly inhibited by 2ml/kg ethanol for up to 3 h following intraperitoneally administration | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Sepharose 4B-L-tyrosine-sulfanilamide affinity chromatography | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Homo sapiens | - |
| erythrocyte | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CO2 + H2O | - |
Homo sapiens | H2CO3 | - |
r | |
| CO2 + H2O | - |
Rattus norvegicus | H2CO3 | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CA-I | isozyme | Homo sapiens |
| CA-II | isozyme | Homo sapiens |
| carbonic anhydrase | - |
Rattus norvegicus |
| carbonic anhydrase-I | isozyme | Homo sapiens |
| carbonic anhydrase-II | isozyme | Homo sapiens |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 1830 | - |
isozyme carbonic anhydrase-II | Homo sapiens | ethanol | |
| 2090 | - |
isozyme carbonic anhydrase-I | Homo sapiens | ethanol | |
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