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Literature summary for 4.2.1.1 extracted from

  • Maupin, C.M.; Saunders, M.G.; Thorpe, I.F.; McKenna, R.; Silverman, D.N.; Voth, G.A.
    Origins of enhanced proton transport in the Y7F mutant of human carbonic anhydrase II (2008), J. Am. Chem. Soc., 130, 11399-11408.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
Y7F the mutation has the effect of increasing the proton transfer rate by 7fold in the dehydration direction of the enzyme reaction compared to the wild type enzyme Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ contains zinc Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P00918
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO2 + H2O
-
Homo sapiens H2CO3
-
r

Synonyms

Synonyms Comment Organism
CA II
-
Homo sapiens
carbonic anhydrase II
-
Homo sapiens