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Literature summary for 4.2.1.1 extracted from

  • Bertucci, A.; Innocenti, A.; Zoccola, D.; Scozzafava, A.; Allemand, D.; Tambutte, S.; Supuran, C.T.
    Carbonic anhydrase inhibitors: inhibition studies of a coral secretory isoform with inorganic anions (2009), Bioorg. Med. Chem. Lett., 19, 650-653.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
acetazolamide
-
Stylophora pistillata
azide
-
Stylophora pistillata
bicarbonate
-
Stylophora pistillata
bisulfite
-
Stylophora pistillata
bromide best inhibitor Stylophora pistillata
Carbonate best inhibitor Stylophora pistillata
chloride
-
Stylophora pistillata
Cyanate
-
Stylophora pistillata
ethoxzolamide
-
Stylophora pistillata
fluoride
-
Stylophora pistillata
hydrogen sulfide
-
Stylophora pistillata
Iodide best inhibitor Stylophora pistillata
isocyanide
-
Stylophora pistillata
nitrate
-
Stylophora pistillata
nitrite
-
Stylophora pistillata
phenylarsonic acid
-
Stylophora pistillata
phenylboronic acid
-
Stylophora pistillata
sulfamate best inhibitor Stylophora pistillata
sulfamic acid
-
Stylophora pistillata
sulfate slight inhibition Stylophora pistillata
thiocyanate
-
Stylophora pistillata

Organism

Organism UniProt Comment Textmining
Stylophora pistillata
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO2 + H2O
-
Stylophora pistillata H2CO3
-
r

Synonyms

Synonyms Comment Organism
carbonic anhydrase
-
Stylophora pistillata

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000016
-
acetazolamide at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.009
-
Iodide at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.0097
-
bromide at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.01
-
bisulfite at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.41
-
hydrogen sulfide at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.41
-
sulfamate at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.45
-
bicarbonate at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.45
-
Carbonate at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.5
-
chloride at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.52
-
azide at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.56
-
nitrate at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.58
-
Cyanate at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.59
-
isocyanide at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.62
-
fluoride at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.68
-
thiocyanate at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.68
-
phenylboronic acid at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.77
-
nitrite at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.78
-
phenylarsonic acid at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.81
-
sulfamic acid at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata
0.91
-
sulfate at 20°C and pH 7.5 in 10 mM HEPES buffer Stylophora pistillata