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BRENDA support

Literature summary for 4.2.1.1 extracted from

  • Gao, B.B.; Clermont, A.; Rook, S.; Fonda, S.J.; Srinivasan, V.J.; Wojtkowski, M.; Fujimoto, J.G.; Avery, R.L.; Arrigg, P.G.; Bursell, S.E.; Aiello, L.P.; Feener, E.P.
    Extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation (2007), Nat. Med., 13, 181-188.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
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Homo sapiens
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-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation ?
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens P00915
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-

Source Tissue

Source Tissue Comment Organism Textmining
vitreous chamber elevated levels of extracellular carbonic anhydrase-I (CA-I) in vitreous from individuals with diabetic retinopathy, suggesting that retinal hemorrhage and erythrocyte lysis contribute to the diabetic vitreous proteome Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information extracellular carbonic anhydrase mediates hemorrhagic retinal and cerebral vascular permeability through prekallikrein activation Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
carbonic anhydrase-I
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Homo sapiens