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Literature summary for 4.2.1.1 extracted from
- Bile acid derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide as new carbonic anhydrase inhibitors: Synthesis and investigation of inhibition effects (2002), Bioorg. Med. Chem., 10, 2561-2567.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3alpha,12alpha-diacetoxy-5beta-cholan-24-oic acid | - |
Homo sapiens |  |
| 3alpha,7alpha,12alpha-triacetoxy-5beta-cholan-24-oic acid | - |
Homo sapiens | |
| 3alpha-acetoxy-5beta-cholan-24-oic acid | - |
Homo sapiens | |
| 5-(3,7,12-trioxo-5beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide | - |
Homo sapiens | |
| 5-(3alpha,12alpha-dihydroxy-5beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide | - |
Homo sapiens | |
| 5-(3alpha,7alpha,12alpha-triacetoxy-5beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide | - |
Homo sapiens | |
| 5-(3alpha,7alpha,12alpha-trihydroxy-5beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide | - |
Homo sapiens | |
| 5-(3alpha-acetoxy-5beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide | - |
Homo sapiens | |
| 5-(3alpha-hydroxy-5beta-cholanamido)-1,3,4-thiadiazole-2-sulfonamide | - |
Homo sapiens | |
| 5-amino-1,3,4-thiadiazole-2-sulfonamide | - |
Homo sapiens | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Zn2+ | zinc-metalloenzyme | Homo sapiens | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| H2CO3 | Homo sapiens | - |
CO2 + H2O | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood | - |
Homo sapiens | - |
| erythrocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| H2CO3 | - |
Homo sapiens | CO2 + H2O | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| carbonic anhydrase | - |
Homo sapiens |
| HCA-I | - |
Homo sapiens |
| HCA-II | - |
Homo sapiens |
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