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Literature summary for 4.2.1.1 extracted from

  • Hurt, J.D.; Tu, C.; Laipis, P.J.; Silverman, D.N.
    Catalytic properties of murine carbonic anhydrase IV (1997), J. Biol. Chem., 272, 13512-13518.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Mus musculus

Protein Variants

Protein Variants Comment Organism
His64Ala 100fold lower activity compared to the wild type enzyme Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
ethoxyzolamide
-
Mus musculus
OCN-
-
Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
Balb/c lung carbonic anhydrase IV
-

Source Tissue

Source Tissue Comment Organism Textmining
lung Balb/c lung carbonic anhydrase IV Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO2 + H2O
-
Mus musculus H2CO3
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
18300
-
CO2 carbonic anhydrase IV, pH above 9 Mus musculus