Literature summary for 4.2.1.1 extracted from

Kararli, T.; Silverman, D.N.
Inhibition of the hydration of CO2 catalyzed by carbonic anhydrase III from cat muscle (1985), J. Biol. Chem., 260, 3484-3489.

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Inhibitors

Inhibitors	Comment	Organism	Structure
I-	uncompetitive at pH 6.0, mixed type at higher pH-values	Felis catus
N3-	NaN3, uncompetitive at pH 6.0, mixed type at higher pH-values	Felis catus

Organism

Organism	UniProt	Comment	Textmining
Felis catus	-	carbonic anhydrase III	-

Reaction

Reaction	Comment	Organism	Reaction ID
H2CO3 = CO2 + H2O	carbonic anhydrase III is limited in rate by a step occuring outside the actual interconversion of CO2 and HCO3- and involving a change in bonding to hydrogen exchangeable with solvent water	Felis catus	a

Source Tissue

Source Tissue	Comment	Organism	Textmining
muscle	-	Felis catus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CO2 + H2O	-	Felis catus	H2CO3	-	?

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
2000	-	CO2	pH 6-8	Felis catus
10000	-	CO2	above pH 8	Felis catus

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Release 2023.1 (January 2023)