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Literature summary for 4.1.99.13 extracted from
- Light-induced conformational change and product release in DNA repair by (6-4) photolyase (2011), J. Am. Chem. Soc., 133, 2183-2191.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Xenopus laevis | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA) | time-resolved measurements are performed of radical formation, diffusion, and protein conformational changes during light-dependent repair by full-length (6-4) photolyase on DNA carrying a single UV-induced damage. The (6-4) photolyase shows significant volume changes after blue-light activation, indicating protein conformational changes distant from the flavin cofactor. A drastic diffusion change is observed only in the presence of both (6-4) photolyase and damaged DNA, and not for (6-4) photolyase alone or with undamaged DNA | Xenopus laevis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| (6-4) photolyase | - |
Xenopus laevis |
| (6-4) PHR | - |
Xenopus laevis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | - |
Xenopus laevis |  |
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