Crystallization (Comment) | Organism |
---|---|
two crystal structures of the (6-4) photolyase bound to lesion containing DNA before and after repair, repair does not involve oxetane formation before light-induced electron transfer. The histidine 369, supposed to activate the acylimine, is in a position that does not allow efficient proton donation and hence activation of this substructure | Drosophila melanogaster |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | O48652 | - |
- |
Drosophila melanogaster | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
T(6-4)T photoproduct (in DNA) | - |
Drosophila melanogaster | 2 thymidine residues (in DNA) | - |
? |
Synonyms | Comment | Organism |
---|---|---|
(6-4) photolyase | - |
Drosophila melanogaster |
(6-4) photolyase | - |
Arabidopsis thaliana |
(6-4)-Phr | - |
Drosophila melanogaster |
(6-4)-Phr | - |
Arabidopsis thaliana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
8-hydroxy-5-deazariboflavin | - |
Drosophila melanogaster | |
FAD | in the structure of (6-4) photolyase, there is a phosphate anion bound to Glu-243 and Trp-238, close to FAD | Arabidopsis thaliana |