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Literature summary for 4.1.99.1 extracted from

  • Yoshida, H.; Kumagai, H.; Yamada, H.
    Catalytic properties of tryptophanase from Proteus rettgeri (1974), Agric. Biol. Chem., 38, 463-464.
No PubMed abstract available
Search for more literature for 4.1.99.1

Inhibitors

Inhibitors Comment Organism Structure
Ala D-Ala; L-Ala Providencia rettgeri
indole
-
 Providencia rettgeri
Phe L-Phe Providencia rettgeri

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.26
-
 L-Trp
-
 Providencia rettgeri
1
-
 L-Cys alpha,beta-elimination Providencia rettgeri
1.8
-
 5-methyl-L-Trp alpha,beta-elimination Providencia rettgeri
2.7
-
 5-hydroxy-L-Trp alpha,beta-elimination Providencia rettgeri
2.8
-
 L-Cys beta-replacement reaction Providencia rettgeri
3.1
-
 S-methyl-L-Cys beta-replacement reaction Providencia rettgeri
4
-
 indole beta-replacement reaction Providencia rettgeri
4.1
-
 indole reverse of alpha,beta-elimination Providencia rettgeri
5
-
 S-methyl-L-Cys alpha,beta-elimination Providencia rettgeri
10
-
 pyruvate cosubstrate indole, alpha,beta-addition Providencia rettgeri

Organism

Organism UniProt Comment Textmining
Providencia rettgeri
-
 AJ2770
-
Providencia rettgeri AJ2770
-
 AJ2770
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-hydroxyindole + L-Cys
-
 Providencia rettgeri 5-hydroxy-L-Trp + ?
-
 ?
5-hydroxyindole + S-methyl-L-Cys
-
 Providencia rettgeri 5-hydroxy-L-Trp + ?
-
 ?
5-methylindole + L-Cys
-
 Providencia rettgeri 5-methyl-L-Trp + ?
-
 ?
5-methylindole + S-methyl-L-Cys
-
 Providencia rettgeri 5-methyl-L-Trp + ?
-
 ?
Cys + H2O L-Cys Providencia rettgeri ?
-
 ?
Cys + H2O L-Cys Providencia rettgeri AJ2770 ?
-
 ?
indole + L-Cys beta-replacement reaction Providencia rettgeri L-Trp + ?
-
 ?
indole + L-Cys beta-replacement reaction Providencia rettgeri AJ2770 L-Trp + ?
-
 ?
indole + pyruvate + NH4+
-
 Providencia rettgeri L-Trp + H2O
-
 ?
indole + pyruvate + NH4+
-
 Providencia rettgeri AJ2770 L-Trp + H2O
-
 ?
indole + S-methyl-L-Cys beta-replacement reaction Providencia rettgeri L-Trp + ?
-
 ?
indole + S-methyl-L-Cys beta-replacement reaction Providencia rettgeri AJ2770 L-Trp + ?
-
 ?
L-Trp + H2O
-
 Providencia rettgeri indole + pyruvate + NH4+
-
 ?
S-methyl-L-Cys + H2O
-
 Providencia rettgeri ?
-
 ?
S-methyl-L-Cys + H2O
-
 Providencia rettgeri AJ2770 ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5 9.5 synthesis of L-Trp from indole and L-Cys or S-methyl-L-Cys Providencia rettgeri
9
-
 synthesis of L-Trp from indole, NH4+ and pyruvate Providencia rettgeri

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate dependent on Providencia rettgeri