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Literature summary for 4.1.3.46 extracted from

  • Chen, M.; Huang, X.; Zhong, C.; Li, J.; Lu, X.
    Identification of an itaconic acid degrading pathway in itaconic acid producing Aspergillus terreus (2016), Appl. Microbiol. Biotechnol., 100, 7541-7548 .
    View publication on PubMed
Search for more literature for 4.1.3.46

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli BL21 (DE3) Aspergillus terreus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
citramalyl-CoA Aspergillus terreus
-
 acetyl-CoA + pyruvate
-
 ?
citramalyl-CoA Aspergillus terreus LYT10
-
 acetyl-CoA + pyruvate
-
 ?

Organism

Organism UniProt Comment Textmining
Aspergillus terreus A0A172MLA1
-
-
Aspergillus terreus LYT10 A0A172MLA1
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Aspergillus terreus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
citramalyl-CoA
-
 Aspergillus terreus acetyl-CoA + pyruvate
-
 ?
citramalyl-CoA
-
 Aspergillus terreus LYT10 acetyl-CoA + pyruvate
-
 ?

Synonyms

Synonyms Comment Organism
CclA
-
 Aspergillus terreus
citramalyl-CoA lyase
-
 Aspergillus terreus

Expression

Organism Comment Expression
Aspergillus terreus upregulated at both transcription and protein levels When 40 g/l of exogenous itaconic acid is added into the medium at the beginning of fermentation up

General Information

General Information Comment Organism
metabolism the enzyme is involved in the catabolic pathway of itaconic acid Aspergillus terreus