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Literature summary for 4.1.3.4 extracted from

  • Messner, B.; Eggerer, H.; Cornforth, J.W.; Mallaby, R.
    Substrate stereochemistry of the hydroxymethylglutaryl-CoA lyase and methylglutaconyl-CoA hydratase reactions (1975), Eur. J. Biochem., 53, 255-264.
No PubMed abstract available
Search for more literature for 4.1.3.4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-3-Hydroxy-3-methylglutaryl-CoA Bos taurus leucine catabolism ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
 bovine
-

Reaction

Reaction Comment Organism Reaction ID
(S)-3-Hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate enzyme is stereospecific and proceeds with inversion of configuration Bos taurus
a

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.3
-
-
 Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-3-Hydroxy-3-methylglutaryl-CoA leucine catabolism Bos taurus ?
-
 ?