Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Streptomyces sp. |
Protein Variants | Comment | Organism |
---|---|---|
additional information | a mutant with pabC-1 inactivated still retains about 20% of the wild type level of antibiotic FR-008 production, pabC-1/pabC-2 double mutation severely reduces antibiotic FR-008 production and renders the mutant p-aminobenzoic acid-auxotrophic | Streptomyces sp. |
additional information | pabC-1/pabC-2 double mutation severely reduces antibiotic FR-008 production and renders the mutant p-aminobenzoic acid-auxotrophic | Streptomyces sp. |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces sp. | - |
- |
- |
Streptomyces sp. | B8Y8J0 | PabC-2 | - |
Streptomyces sp. FR-008 | - |
- |
- |
Streptomyces sp. FR-008 | B8Y8J0 | PabC-2 | - |
Purification (Comment) | Organism |
---|---|
nickel affinity column chromatography | Streptomyces sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-amino-4-deoxychorismate | - |
Streptomyces sp. | 4-aminobenzoate + pyruvate | - |
? | |
4-amino-4-deoxychorismate | - |
Streptomyces sp. FR-008 | 4-aminobenzoate + pyruvate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
4-amino-4-deoxychorismate lyase | - |
Streptomyces sp. |
ADC lyase | - |
Streptomyces sp. |
PabC-1 | - |
Streptomyces sp. |
PabC-2 | - |
Streptomyces sp. |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Streptomyces sp. |