Literature summary for 4.1.3.36 extracted from

Lannergard, J.; von Eiff, C.; Sander, G.; Cordes, T.; Seggewiss, J.; Peters, G.; Proctor, R.A.; Becker, K.; Hughes, D.
Identification of the genetic basis for clinical menadione-auxotrophic small-colony variant isolates of Staphylococcus aureus (2008), Antimicrob. Agents Chemother., 52, 4017-4022.

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Application

Application	Comment	Organism
medicine	mutations in the menB gene, the gene encoding naphthoate synthase, cause the small-colony variant phenotype, small-colony variants are associated with persistent infections and may be selectively enriched during antibody therapy	Staphylococcus aureus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
o-succinylbenzoyl-CoA	Staphylococcus aureus	-	1,4-dihydroxy-2-naphthoyl-CoA + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Staphylococcus aureus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
o-succinylbenzoyl-CoA	-	Staphylococcus aureus	1,4-dihydroxy-2-naphthoyl-CoA + H2O	-	?

Synonyms

Synonyms	Comment	Organism
naphthoate synthase	-	Staphylococcus aureus

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Release 2023.1 (January 2023)