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Literature summary for 4.1.3.32 extracted from

  • Chotpatiwetchkul, W.; Jongkon, N.; Hannongbua, S.; Gleeson, M.P.
    QM/MM investigation of the reaction rates of substrates of 2,3-dimethylmalate lyase A catabolic protein isolated from Aspergillus niger (2016), J. Mol. Graph. Model., 68, 29-38 .
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ activates Aspergillus niger

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2R,3S)-2,3-dimethylmalate Aspergillus niger
-
propanoate + pyruvate
-
?

Organism

Organism UniProt Comment Textmining
Aspergillus niger
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2R)-methylmalate
-
Aspergillus niger ?
-
?
(2R,3S)-2,3-dimethylmalate
-
Aspergillus niger propanoate + pyruvate
-
?
(S)-malate
-
Aspergillus niger ?
-
?
3,3-difluorooxaloacetate
-
Aspergillus niger ?
-
?
oxaloacetate
-
Aspergillus niger oxalate + acetate
-
?

Synonyms

Synonyms Comment Organism
DMML
-
Aspergillus niger

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.00001
-
(S)-malate kcat less than 0.00001 sec-1, pH and temperature not specified in the publication Aspergillus niger
0.00001
-
3,3-difluorooxaloacetate kcat less than 0.00001 sec-1, pH and temperature not specified in the publication Aspergillus niger
0.48
-
oxaloacetate pH and temperature not specified in the publication Aspergillus niger
2.6
-
(2R)-methylmalate pH and temperature not specified in the publication Aspergillus niger
19.2
-
(2R,3S)-2,3-dimethylmalate pH and temperature not specified in the publication Aspergillus niger